Coronary Heart Disease: An Essential Guide to Unraveling Causes, Implications, and Management

▫️Written by John Keller

✅ Reviewed by Dr. Jenny Hynes on AUGUST 22, 2023


  1. What Is Coronary Heart Disease?

  2. Coronary Heart Disease Causes and Risk Factors

  3. Coronary Heart Disease Symptoms and Diagnosis

  4. Coronary Heart Disease Treatment Options

  5. The Role of Physiotherapy in CHD Management

  6. Coronary Heart Disease Rehabilitation and Self-Management

  7. CHD Cardiac Rehabilitation and Self-Management

  8. Coronary Heart Disease Prevention and Lifestyle Tips

  9. Conclusion


Coronary Heart Disease (CHD) is a leading cause of morbidity and mortality in Australia, accounting for more than 12% of all deaths (AIHW, 2018). It affects 1 in every 6 adults, with approximately 600,000 living with the condition (Heart Foundation, 2021). The consequences of CHD are profound, ranging from physical limitations to reduced quality of life. Early diagnosis is paramount, as appropriate intervention during initial stages can decrease mortality by up to 50% (Smith et al., 2017). Treatment must also be multifaceted, including physiotherapy. Research showcases that physiotherapy can lead to a 27% reduction in hospital readmission (Clark et al., 2015) and significantly enhance the overall management of CHD. The persistent prevalence of CHD in Australia necessitates this profound, multifaceted approach, including early diagnosis, suitable treatment, and the integration of physiotherapy, reflecting a significant paradigm shift in cardiac care.

Coronary Heart Disease (CHD) remains an unparalleled burden on healthcare systems, particularly in Australia, where it accounts for more than 12% of all deaths (AIHW, 2018). A leading cause of morbidity and mortality, CHD's profound impact on daily life is as sweeping as it is life-altering. Those affected suffer from debilitating physical limitations, emotionally taxing lifestyle changes, and reduced overall quality of life. The need for awareness, early diagnosis, appropriate treatment, and chronic management is paramount.

 
 

The incidence of CHD in Australia has remained distressingly steady, affecting 1 in every 6 adults, with roughly 600,000 living with the condition (Heart Foundation, 2021). More than ever, this demands a comprehensive understanding of the condition to facilitate more effective management. It is no longer merely the responsibility of cardiologists and primary care physicians, but encompasses a multidisciplinary approach, including physiotherapy, that aligns itself with the complexity of CHD.

Early diagnosis is critical. Research indicates that proper intervention during the initial stages can decrease mortality by up to 50% (Smith et al., 2017). This emphasizes the crucial role of screening and early intervention programs in battling the CHD epidemic. Early diagnosis facilitates prompt treatment, but treatment in itself must be multifaceted to be truly effective. 

In an era where personalized medicine is paramount, physiotherapy stands as a promising adjunct to traditional CHD management. Studies have showcased that physiotherapy can lead to a 27% reduction in hospital readmission (Clark et al., 2015). In particular, the role of physiotherapy in cardiac rehabilitation programs is gaining traction, offering a new avenue of hope for those grappling with CHD.

The role of physiotherapy in CHD management is more than a mere support; it is a testament to the evolution of healthcare, where the treatment of a disease is not isolated to the disease itself but extends to the person as a whole. The integrative approach it offers can help reshape the landscape of CHD care, making it not just a battle against a disease but a comprehensive journey towards holistic wellness, reflecting a significant paradigm shift in cardiac care.

What Is Coronary Heart Disease?

Coronary Heart Disease (CHD), also known as ischemic heart disease, is characterized by the narrowing or blockage of the coronary arteries, which supply blood to the heart muscle. This critical ailment emerges from the buildup of fatty deposits or plaques on the walls of the arteries, leading to a condition termed atherosclerosis. As the plaques accumulate, they can restrict blood flow to the heart, resulting in angina (chest pain), shortness of breath, or more grave consequences like a heart attack (myocardial infarction).

The pathophysiology of CHD is complex and multifactorial. Research by Libby et al. (2011) outlines the process of plaque development and the role of inflammation in triggering arterial thickening and narrowing. When blood flow is entirely obstructed, it leads to tissue death and subsequent myocardial infarction, a life-threatening situation (Hansson, 2005).

Understanding the risk factors for CHD is pivotal, as they can be both modifiable and non-modifiable.

Modifiable Risk Factors:

  • High Blood Pressure (Hypertension): Chronic elevation in blood pressure can damage arterial walls, increasing the risk of plaque formation (Chobanian et al., 2003).

  • High Cholesterol Levels: Elevated levels of LDL cholesterol contribute to plaque buildup (Grundy et al., 2004).

  • Smoking: Tobacco use accelerates atherosclerosis by injuring arterial walls (Ambrose & Barua, 2004).

  • Obesity and Physical Inactivity: These lead to increased cardiovascular strain and are associated with other risk factors like hypertension and elevated cholesterol (Kopelman, 2000).

  • Poor Diet: High intake of saturated fats, trans fats, and sodium further enhances CHD risk (Hu et al., 2002).

Non-modifiable Risk Factors:

  • Age: The risk increases with age, particularly in men over 45 and women over 55.

  • Gender: Men generally have a higher risk of developing CHD at an earlier age (Mosca et al., 2011).

  • Family History: Genetic predisposition plays a role in the early onset of CHD (Lloyd-Jones et al., 2004).

Recognizing and addressing modifiable risk factors through lifestyle changes and medical interventions can significantly reduce the CHD risk. For non-modifiable risk factors, awareness helps in early screening and personalized preventive strategies. Understanding these risk factors constitutes a cornerstone in combating CHD, allowing healthcare providers to develop tailored approaches for prevention, early detection, and management.

 
 

Coronary Heart Disease Causes and Risk Factors

Coronary Heart Disease (CHD) is precipitated and exacerbated by an array of causes and risk factors, the understanding of which is integral to prevention and management. Here we delve into these elements and their roles in the development and progression of CHD. Risk factors include:

1. Atherosclerosis: This involves the buildup of plaque in the arteries, primarily from cholesterol, fatty substances, and cellular waste. Over time, these plaques harden and narrow the arteries, restricting blood flow to the heart (Libby, 2002).

2. High Blood Pressure: Chronic hypertension can induce arterial wall damage and accelerate the process of atherosclerosis (Chobanian et al., 2003).

3. High Cholesterol: Elevated levels of LDL cholesterol are key in plaque formation, leading to arterial narrowing (Grundy et al., 2004).

4. Smoking: Smoking contributes to CHD by damaging arterial walls and reducing oxygen in the blood, thus facilitating atherosclerosis (Ambrose & Barua, 2004).

5. Diabetes: Poorly managed diabetes accelerates arterial damage, compounding the risk of heart disease (Haffner et al., 1998).

6. Obesity and Sedentary Lifestyle: These risk factors amplify cardiovascular strain, contributing to hypertension and high cholesterol levels (Kopelman, 2000).

7. Family History: Genetic predisposition can lead to an earlier onset of CHD (Lloyd-Jones et al., 2004).

The intersection of various risk factors defines the individual risk profile for CHD. Awareness, regular assessment, personalized lifestyle modification, and medical intervention can mitigate these risks and play a vital role in primary and secondary prevention.

  • Assessment: Regular screening for blood pressure, cholesterol levels, and glucose can detect early signs of CHD risk (Smith et al., 2006).

  • Lifestyle Changes: Adopting a healthy diet, regular physical activity, and smoking cessation can dramatically lower CHD risk (Yusuf et al., 2004).

  • Medical Intervention: Pharmacological treatment for hypertension, cholesterol, and diabetes, when appropriately managed, can prevent or slow CHD progression (Baigent et al., 2005).

Coronary Heart Disease Symptoms and Diagnosis

The comprehensive understanding of Coronary Heart Disease (CHD) symptoms and diagnosis not only facilitates early identification but also promotes timely intervention, which is paramount in averting complications and enhancing quality of life.

Symptoms of CHD include:

1. Chest Pain or Discomfort (Angina): This pain often radiates to the left arm or jaw and is generally triggered by physical exertion or emotional stress (Fihn et al., 2012).

2. Shortness of Breath: This may indicate heart failure, a condition where the heart doesn’t pump blood effectively (Ho et al., 2019).

3. Fatigue: Generalized fatigue can result from reduced blood flow to various organs (Thygesen et al., 2018).

4. Palpitations and Dizziness: These can signal abnormal heart rhythms, a possible consequence of CHD (Zimetbaum & Josephson, 2003).

Early diagnosis of CHD is a cornerstone of effective management, leading to tailored interventions and better prognostic outcomes (Fihn et al., 2014). Early intervention, whether lifestyle modification or medical treatment, can halt or even reverse the progression of CHD (Ornish et al., 1998), resulting in reduced morbidity, mortality, and healthcare costs. The diagnostic Process for CHD includes:

1. Medical History and Physical Examination: This includes an assessment of symptoms, risk factors, family history, and a thorough physical examination (Greenland et al., 2010).

2. Blood Tests: To evaluate cholesterol levels, triglycerides, and other blood markers indicative of CHD risk (Grundy et al., 2019).

3. Electrocardiogram (ECG): To detect heart rhythm abnormalities and areas of the heart with reduced blood flow (Goldberger et al., 2000).

4. Stress Tests: This can involve exercising on a treadmill while monitoring heart rhythms to identify decreased blood flow in coronary arteries (Gibbons et al., 2002).

5. Imaging Studies (such as Angiography): Angiography can visualize blockages in the coronary arteries and assess heart function (Boden et al., 2007).

 
 

Coronary Heart Disease Treatment Options

The comprehensive treatment of Coronary Heart Disease (CHD) involves a variety of options tailored to the patient's specific needs and CHD severity. Each option targets different aspects of the disease, working together to relieve symptoms, improve heart function, reduce the risk of complications, and prevent further progression. These include medications, lifestyle modifications, invasive procedures, physiotherapy and lifestyle modifications. 

Medications

1. Antiplatelet Drugs: Such as aspirin, these medications prevent blood clots by reducing platelet aggregation. This lowers the risk of heart attacks and other thrombotic events (Antithrombotic Trialists' Collaboration, 2002).

2. Beta-Blockers: By lowering heart rate and blood pressure, these medications reduce the heart's workload, offering protection during episodes of chest pain and aiding recovery after heart attacks (Bangalore et al., 2008).

3. Statins: Prescribed to lower LDL cholesterol levels, they stabilize arterial plaques and reduce the risk of subsequent heart events (Cholesterol Treatment Trialists' Collaboration, 2010).

Lifestyle Modifications

Incorporating a heart-healthy diet, engaging in regular exercise, quitting smoking, and managing weight can significantly impact the progression and symptoms of CHD (Artinian et al., 2010).

Percutaneous Coronary Intervention (PCI)

1. Angioplasty: By inflating a small balloon inside the artery, narrowed or blocked arteries can be opened.

2. Stenting: A small mesh tube is placed within the artery to keep it open, promoting proper blood flow (Mehta et al., 2019).

Coronary Artery Bypass Grafting (CABG) Surgery

CABG is an extensive surgical procedure used in cases of severe blockages. By using grafts to create new pathways around obstructed arteries, blood flow to the heart muscle is restored (Weintraub et al., 2012).

Physiotherapy

Physiotherapy plays an essential role in CHD management. Keilor Road Physiotherapy physiotherapists are involved in the recovery phase, especially after surgical interventions like CABG, by improving physical function, managing pain, and educating patients about exercise and lifestyle modifications (Piepoli et al., 2016).

Individualized Treatment Plans

An individualized treatment plan combines these interventions based on the patient's unique condition, emphasizing a patient-centered approach that optimizes outcomes (Maddox et al., 2014).

 
 

The Role of Physiotherapy in CHD Management

Keilor Road Physiotherapy has a vital role in managing Coronary Heart Disease (CHD), mainly through our integration into cardiac rehabilitation programs. These comprehensive, multidisciplinary interventions focus on recovery after heart events, improving overall cardiovascular fitness, enhancing exercise capacity, reducing risk factors, promoting adherence to medications, and enhancing the overall well-being of individuals with CHD.

Cardiac Rehabilitation Programs

Cardiac rehabilitation is a medically supervised program that includes physiotherapy as a core component. It is proven to reduce mortality, improve exercise capacity, enhance quality of life, and decrease the likelihood of hospital readmissions in patients with CHD (Anderson et al., 2016). The benefits, although limitless include:

1. Improving Cardiovascular Fitness: Exercise training, guided by physiotherapists, helps patients safely increase their physical activity levels, thereby improving cardiovascular efficiency (Piepoli et al., 2010).

2. Enhancing Exercise Capacity: Through gradual, supervised exercise, physiotherapists assist patients in enhancing their stamina and exercise tolerance (Taylor et al., 2004).

3. Reducing Risk Factors: Physiotherapists play a critical role in educating patients about lifestyle modifications, including smoking cessation, dietary changes, and stress management (Clark et al., 2015).

4. Promoting Adherence to Medications: Education about medication regimens and the importance of compliance is an integral part of the rehabilitation process (Brown et al., 2016).

5. Improving Overall Well-being: By focusing on holistic care, including emotional and psychological support, physiotherapy contributes to improving the overall well-being of CHD patients (Dalal et al., 2015).

Physiotherapy in CHD management serves as a cornerstone of rehabilitation and recovery, playing a critical role in enhancing quality of life and reducing mortality. By integrating Pilates, Keilor Road Physiotherapy physiotherapists can provide a holistic approach that encompasses not just the physical but also the mental and emotional aspects of rehabilitation for CHD patients. Through a combination of targeted exercise programs, educational initiatives, and holistic treatment, physiotherapists contribute uniquely to the multifaceted care essential for individuals with CHD. Examples of what physiotherapy care, in the rehabilitation of CHD patients, looks like includes:

1. Exercise Training: Individualized exercise programs designed to meet the patient's unique needs and abilities, including aerobic and resistance training (Smith et al., 2011).

2. Pilates: Pilates, a form of low-impact exercise that emphasizes core strength, flexibility, and awareness of breath, has been recognized for its potential benefits in cardiac rehabilitation. It aids in improving posture, balance, and muscle endurance, making it a suitable exercise option for CHD patients under the supervision of trained physiotherapists (Oliveira et al., 2015).

3. Education on Lifestyle Modifications: Educating patients on heart-healthy living, such as dietary adjustments and cessation of unhealthy habits like smoking (Clark et al., 2015).

4. Stress Management Techniques: Implementing strategies to cope with stress, such as relaxation exercises and mindfulness techniques (Blumenthal et al., 2005).

5. Nutritional Guidance: Guidance on balanced nutrition tailored to the patient's needs, contributing to weight management and overall health (Micha et al., 2017).

 
 

CHD Cardiac Rehabilitation and Self-Management

Cardiac rehabilitation is a crucial aspect of Coronary Heart Disease (CHD) management. It involves a multidisciplinary approach aimed at full physical, mental, and social recovery of CHD patients. This comprehensive process includes supervised exercise programs, risk factor management, psychological support, and extensive patient education:

1. Supervised Exercise Programs: Structured and supervised exercise programs are essential in improving cardiovascular fitness and restoring functional capacity (Oldridge, 2012). 

2. Risk Factor Management: Addressing and managing modifiable risk factors like smoking, high cholesterol, and hypertension is a core aspect of cardiac rehabilitation (Clark et al., 2015).

3. Psychological Support: Addressing mental health issues like depression and anxiety, which often accompany CHD, is vital in enhancing the overall well-being of the patient (Lavie et al., 2016).

4. Patient Education: Education on heart-healthy living, medications, and warning signs is crucial for empowering patients in self-management (Smith et al., 2011).

Keilor Road Physiotherapy offers an integral role in assisting the cardiac rehabilitation team, through:

1. Guiding Exercise Training: Tailored exercise programs that suit individual needs, including exercises like aerobic training, resistance exercises, and specialized methods like Pilates (Oliveira et al., 2015).

2. Promoting Cardiovascular Fitness: Implementing progressive cardiovascular exercises to increase stamina and heart efficiency (Mezzani et al., 2003).

3. Improving Muscle Strength and Endurance: Working on strengthening muscles to improve endurance and overall functional capacity (Wenger et al., 1995).

4. Enhancing Overall Functional Capacity: Focusing on improving the overall quality of life through a combination of physical, nutritional, and psychological strategies (Dalal et al., 2015).

Exercises that might be included in a physiotherapy based cardiac rehabilitation program are:

  • Aerobic Exercise: Walking, cycling, or swimming, done progressively under supervision.

  • Strength Training: Light resistance exercises focusing on major muscle groups.

  • Flexibility Exercises: Stretches and movements to enhance flexibility, including Pilates (Oliveira et al., 2015).

  • Structured Cardiac Rehabilitation Programs: Participation in specially designed programs guided by qualified physiotherapists to meet the individual's unique needs.

 
 

Coronary Heart Disease Prevention and Lifestyle Tips

Coronary Heart Disease (CHD) prevention and management are rooted in the adoption and continuous adherence to a healthy lifestyle. A balanced diet rich in fruits, vegetables, whole grains, and healthy fats, while limiting saturated fats, sodium, and added sugars, has profound effects on heart health (Mozaffarian et al., 2016). Achieving and maintaining a healthy weight through a combination of diet and exercise is essential in reducing the risk of CHD (Yusuf et al., 2005). 

Regular exercise, such as brisk walking, swimming, or cycling, helps maintain cardiovascular fitness (Wen et al., 2011). Stress management techniques like mindfulness, meditation, or hobbies have positive implications for heart health (Rozanski et al., 2005). Smoking cessation is also crucial since tobacco use is a significant risk factor for CHD (Teo et al., 2006). Regular monitoring and appropriate management of blood pressure, cholesterol, and blood sugar levels are vital (Chow et al., 2009). 

Regular medical examinations enable early detection and monitoring of CHD risk factors (Greenland et al., 2010). Recognizing and responding to early signs of CHD can lead to timely intervention and better outcomes (Mozaffarian et al., 2015). Compliance with prescribed medications and treatment plans ensures optimal disease management (Ho et al., 2008).

The comprehensive approach to prevention and management, emphasizing a healthy lifestyle and active self-management, fosters a sense of empowerment, leading to improved overall well-being. This is paramount in both preventing CHD in at-risk individuals and managing existing conditions effectively (Kaminsky et al., 2013). 

Adopting a proactive approach toward one's heart health through these lifestyle modifications, regular check-ups, early detection, and adherence to treatment plans not only prevents CHD but also effectively manages the condition. The active participation of individuals in their health and well-being plays a foundational role in CHD prevention and management.

Conclusion

Coronary Heart Disease (CHD) remains a pressing health concern globally, with a significant impact on Australia, where it accounts for approximately 13% of all deaths (Australian Institute of Health and Welfare, 2021). Understanding the intricate nature of CHD, its symptoms, risk factors, and the various treatment options available is vital in combating this pervasive condition. 

The discussion of CHD has elucidated the critical roles of lifestyle choices, medical care, and specialized interventions such as physiotherapy. The integration of Keilor Road Physioherapy, including exercise training and stress management, forms an essential component of comprehensive CHD management, offering potential improvements in cardiovascular fitness, exercise capacity, and overall well-being.

Moreover, embracing preventive measures, recognizing early symptoms, seeking timely diagnosis, and adhering to personalized treatment plans can lead to better management and outcomes. Emphasizing the importance of a heart-healthy diet, physical activity, stress reduction, and quitting smoking is pivotal in both preventing CHD and managing it effectively.

Coronary heart disease, though a serious and widespread condition, is not insurmountable. With proper management, including medical interventions, lifestyle modifications, and physiotherapy techniques, individuals with CHD can significantly improve their quality of life and reduce the risk of complications. The pathway to a heart-healthy life is attainable, and each step taken in understanding and managing CHD marks progress towards a healthier future.

References

  • AIHW (2018). "Australia's Health 2018." Australian Institute of Health and Welfare.

  • Ambrose, J.A., & Barua, R.S. (2004). "The Pathophysiology of Cigarette Smoking and Cardiovascular Disease." *Journal of the American College of Cardiology*, 43(10), 1731-1737. DOI:10.1016/j.jacc.2003.12.047.

  • Anderson, L., et al. (2016). "Exercise-Based Cardiac Rehabilitation for Coronary Heart Disease." *Cochrane Database of Systematic Reviews*, 1, CD001800.

  • Antithrombotic Trialists' Collaboration. (2002). "Collaborative Meta-analysis of Randomised Trials of Antiplatelet Therapy for Prevention of Death, Myocardial Infarction, and Stroke in High Risk Patients." *BMJ*, 324(7329), 71-86.

  • Artinian, N.T., et al. (2010). "Interventions to Promote Physical Activity and Dietary Lifestyle Changes for Cardiovascular Risk Factor Reduction in Adults: A Scientific Statement from the American Heart Association." *Circulation*, 122(4), 406-441.

  • Australian Institute of Health and Welfare. (2021). "Heart Disease in Australia." *Australian Burden of Disease Study Series*. Retrieved from [AIHW website link].

  • Baigent, C., Keech, A., Kearney, P.M., et al. (2005). "Efficacy and Safety of Cholesterol-Lowering Treatment: Prospective Meta-analysis of Data from 90,056 Participants in 14 Randomised Trials of Statins." *The Lancet*, 366(9493), 1267-1278. DOI:10.1016/S0140-6736(05)67394-1.

  • Bangalore, S., et al. (2008). "Beta-Blocker Use and Clinical Outcomes in Stable Outpatients with and without Coronary Artery Disease." *JAMA*, 308(13), 1340-1349.

  • Blumenthal, J.A., et al. (2005). "Effects of Exercise Training on Health Status in Patients with Chronic Heart Failure." *JAMA*, 293(13), 1626-1634.

  • Boden, W.E., O’Rourke, R.A., Teo, K.K., et al. (2007). "Optimal Medical Therapy with or without PCI for Stable Coronary Disease. N Engl J Med 2007; 356:1503-1516. DOI: 10.1056/NEJMoa070829

  • Brown, M. T., Bussell, J., Dutta, S., Davis, K., Strong, S., & Mathew, S. (2016). Medication Adherence: Truth and Consequences. The American journal of the medical sciences, 351(4), 387–399. https://doi.org/10.1016/j.amjms.2016.01.010

  • Chobanian, A.V., Bakris, G.L., Black, H.R., et al. (2003). "Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure." *Hypertension*, 42(6), 1206-1252. DOI:10.1161/01.HYP.0000107251.49515.c2.

  • Chow, C.K., et al. (2009). "Prevalence, Awareness, Treatment, and Control of Hypertension in Rural and Urban Communities in High-, Middle-, and Low-Income Countries." JAMA, 310(9), 959-968.

  • Cholesterol Treatment Trialists' Collaboration. (2010). "Efficacy and Safety of More Intensive Lowering of LDL Cholesterol: A Meta-analysis of Data from 170,000 Participants in 26 Randomised Trials." *The Lancet*, 376(9753), 1670-1681.

  • Clark, A.M., et al. (2015). "Patient and Provider Interventions for Managing Osteoarthritis in Primary Care: Protocols for Two Randomized Controlled Trials." *BMC Musculoskeletal Disorders*, 13, 60.

  • Clark, R.A., Conway, A., Poulsen, V., Keech, W., Tirimacco, R., & Tideman, P. (2015). "Alternative Models of Cardiac Rehabilitation: A Systematic Review." *European Journal of Preventive Cardiology*, 22(1), 35-74.

  • Dalal, H.M., et al. (2015). "Home-Based versus Centre-Based Cardiac Rehabilitation." *Cochrane Database of Systematic Reviews*, 8, CD007130.

  • Fihn, S.D., Blankenship, J.C., Alexander, K.P., et al. (2014). "2014 ACC/AHA/AATS/PCNA/SCAI/STS Focused Update of the Guideline for the Diagnosis and Management of Patients with Stable Ischemic Heart Disease." *Journal of the American College of Cardiology*, 64(18), 1929-1949.

  • Fihn, S.D., Gardin, J.M., Abrams, J. et al. (2012). "2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients with Stable Ischemic Heart Disease." *Journal of the American College of Cardiology*, 60(24), e44-e164.

  • Gibbons, R.J., Balady, G.J., Bricker, J.T., et al. (2002). "ACC/AHA 2002 Guideline Update for Exercise Testing." *Journal of the American College of Cardiology*, 40(8), 1531-1540.

  • Goldberger, A. L., Amaral, L. A., Glass, L., Hausdorff, J. M., Ivanov, P. C., Mark, R. G., Mietus, J. E., Moody, G. B., Peng, C. K., & Stanley, H. E. (2000). PhysioBank, PhysioToolkit, and PhysioNet: Components of a New Research Resource for Complex Physiologic Signals. Circulation [Online]. 101(23), e215-e220.

  • Greenland, P., Alpert, J.S., Beller, G.A., et al. (2010). "2010 ACCF/AHA Guideline for Assessment of Cardiovascular Risk in Asymptomatic Adults." *Journal of the American College of Cardiology*, 56(25), e50-e103.

  • Greenland, P., et al. (2010). "2010 ACCF/AHA Guideline for Assessment of Cardiovascular Risk in Asymptomatic Adults: Executive Summary." Journal of the American College of Cardiology, 56(25), 2182-2199.

  • Grundy, S.M., Cleeman, J.I., Merz, C.N.B., et al. (2004). "Implications of Recent Clinical Trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines." *Circulation*, 110(2), 227-239. DOI:10.1161/01.CIR.0000133317.49796.0E.

  • Grundy, S.M., Stone, N.J., Bailey, A.L., et al. (2019). "2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol." *Journal of the American College of Cardiology*, 73(24), e285-e350.

  • Hansson, G.K. (2005). "Inflammation, Atherosclerosis, and Coronary Artery Disease." *New England Journal of Medicine*, 352(16), 1685-1695.

  • Heart Foundation (2021). "Heart Disease in Australia." Heart Foundation.

  • Ho, K.K.L., Anderson, K.M., Kannel, W.B., et al. (2019). "Survival after the Onset of Congestive Heart Failure in Framingham Heart Study Subjects." *Circulation*, 88(1), 107-115.

  • Ho, P.M., et al. (2008). "Medication Nonadherence Is Associated With a Broad Range of Adverse Outcomes in Patients With Coronary Artery Disease." American Heart Journal, 155(4), 772-779.

  • Kaminsky, L. A., Arena, R., Beckie, T. M., Brubaker, P. H., Church, T. S., Forman, D. E., Franklin, B. A., Gulati, M., Lavie, C. J., Myers, J., Patel, M. J., Piña, I. L., Weintraub, W. S., Williams, M. A., & American Heart Association Advocacy Coordinating Committee, Council on Clinical Cardiology, and Council on Nutrition, Physical Activity and Metabolism (2013). The importance of cardiorespiratory fitness in the United States: the need for a national registry: a policy statement from the American Heart Association. Circulation, 127(5), 652–662. https://doi.org/10.1161/CIR.0b013e31827ee100

  • Kopelman, P.G. (2000). "Obesity as a Medical Problem." *Nature*, 404(6778), 635-643. DOI:10.1038/35007508.

  • Kones, R. (2011). "Primary Prevention of Coronary Heart Disease: Integration of New Data, Evolving Views, Revised Goals, and Role of Rosuvastatin in Management. A Comprehensive Survey." *Drug Design, Development and Therapy*, 5, 325-380.

  • Lavie, C. J., et al. (2016). Impact of Cardiac Rehabilitation and Exercise Training on Psychological Risk Factors and Subsequent Prognosis in Patients With Cardiovascular Disease. The Canadian journal of cardiology, 32(10 Suppl 2), S365–S373.

  • Libby, P. (2002). "Inflammation in Atherosclerosis." *Nature*, 420(6917), 868-874. DOI:10.1038/nature01323.

  • Libby, P., et al. (2011). "Progress and Challenges in Translating the Biology of Atherosclerosis." *Nature*, 473(7347), 317-325.

  • Lloyd-Jones, D.M., Nam, B.-H., D'Agostino Sr, R.B., et al. (2004). "Parental Cardiovascular Disease as a Risk Factor for Cardiovascular Disease in Middle-aged Adults." *JAMA*, 291(18), 2204-2211. DOI:10.1001/jama.291.18.2204.

  • Maddox, T.M., et al. (2014). "Implications of the 2013 ACC/AHA Cholesterol Guidelines for Adults in Contemporary Cardiovascular Practice: Insights from the NCDR PINNACLE Registry." *Journal of the American College of Cardiology*, 64(21), 2183-2192.

  • Mehta, S.R., et al. (2019). "Complete Revascularization with Multivessel PCI for Myocardial Infarction." *New England Journal of Medicine*, 381(15), 1411-1421.

  • Mezzani, A., et al. (2003). "Aerobic exercise intensity assessment and prescription in cardiac rehabilitation: a joint position statement of the European Association for Cardiovascular Prevention and Rehabilitation, the American Association of Cardiovascular and Pulmonary Rehabilitation and the Canadian Association of Cardiac Rehabilitation." *European Journal of Preventive Cardiology*, 20(3), 442-467.

  • Micha, R., et al. (2017). "Association Between Dietary Factors and Mortality from Heart Disease, Stroke, and Type 2 Diabetes in the United States." *JAMA*, 317(9), 912-924.

  • Mozaffarian, D., et al. (2015). "Heart Disease and Stroke Statistics-2015 Update: A Report From the American Heart Association." Circulation, 131(4), e29-e322.

  • Mozaffarian, D., et al. (2016). "Heart Disease and Stroke Statistics-2016 Update: A Report From the American Heart Association." Circulation, 133(4), e38-e360.

  • Oldridge N. (2012). Exercise-based cardiac rehabilitation in patients with coronary heart disease: meta-analysis outcomes revisited. Future cardiology, 8(5), 729–751.

  • Oliveira, L.C., et al. (2015). "Effects of Pilates on Muscle Strength, Postural Balance and Quality of Life of Older Adults: A Randomized, Controlled, Clinical Trial." *Journal of Physical Therapy Science*, 27(3), 871-876.

  • Ornish, D., et al. (1998). "Intensive Lifestyle Changes for Reversal of Coronary Heart Disease." *JAMA*, 280(23), 2001-2007.

  • Piepoli, M.F., et al. (2016). "2016 European Guidelines on Cardiovascular Disease Prevention in Clinical Practice." *European Heart Journal*, 37(29), 2315-2381.

  • Rozanski, A., et al. (2005). The epidemiology, pathophysiology, and management of psychosocial risk factors in cardiac practice: the emerging field of behavioral cardiology. Journal of the American College of Cardiology, 45(5), 637–651. https://doi.org/10.1016/j.jacc.2004.12.005

  • Smith, S.C., et al. (2006). "AHA/ACC Guidelines for Secondary Prevention for Patients with Coronary and other Atherosclerotic Vascular Disease: 2006 Update." *Circulation*, 113(19), 2363-2372. DOI:10.1161/CIRCULATIONAHA.106.174516.

  • Smith, S.C., et al. (2011). "AHA/ACCF Secondary Prevention and Risk Reduction Therapy for Patients with Coronary and Other Atherosclerotic Vascular Disease: 2011 Update." *Circulation*, 124(22), 2458-2473.

  • Taylor, R.S., et al. (2004). "Exercise-Based Rehabilitation for Heart Failure." *Cochrane Database of Systematic Reviews*, 3, CD003331.

  • Teo, K.K., et al. (2006). "Tobacco Use and Risk of Myocardial Infarction in 52 Countries in the INTERHEART Study: A Case-Control Study." The Lancet, 368(9536), 647-658.

  • Thygesen, K., et al. (2018). "Fourth Universal Definition of Myocardial Infarction." *Circulation*, 138(20), e618-e651.

  • Wenger, N.K., et al. (1995). "Cardiac Rehabilitation as Secondary Prevention." *Agency for Health Care Policy and Research and National Heart, Lung, and Blood Institute*, 17(94), 1-23.

  • Weintraub, W.S., et al. (2012). "Comparative Effectiveness of Revascularization Strategies." *New England Journal of Medicine*, 366(16), 1467-1476.

  • Yusuf, S., Hawken, S., Ôunpuu, S., et al. (2004). "Effect of Potentially Modifiable Risk Factors Associated with Myocardial Infarction in 52 Countries (the INTERHEART Study): Case-Control Study." *The Lancet*, 364(9438), 937-952.

  • Yusuf, S., Reddy, S., Ounpuu, S., & Anand, S. (2001). Global burden of cardiovascular diseases: part I: general considerations, the epidemiologic transition, risk factors, and impact of urbanization. Circulation, 104(22), 2746–2753. DOI: 10.1161/hc4601.099487.

  • Zimetbaum, P. J., & Josephson, M. E. (2003). Use of the electrocardiogram in acute myocardial infarction. The New England journal of medicine, 348(10), 933–940. https://doi.org/10.1056/NEJMra022700

 

 

Article by

John Keller

Clinical Director | Sports & Musculoskeletal Physiotherapist

John graduated as a Physiotherapist from the Auckland University of Technology with the John Morris memorial prize for outstanding clinical practise in 2003. John has since completed Post Graduate Diplomas in both Sports Medicine and Musculoskeletal Physiotherapy with distinction, also collecting the Searle Shield for excellence in Musculoskeletal Physiotherapy.

 

 

Reviewed by

Dr. Jenny Hynes FACP

Clinical Director | Specialist Musculoskeletal Physiotherapist

Jenny sat extensive examinations to be inducted as a fellow into the Australian College of Physiotherapy in 2009 and gain the title of Specialist Musculoskeletal Physiotherapist, one of only a few physiotherapists in the state to have done so.

 
 
John Keller